Endocrine Abstracts

Klinefelter syndrome (KS; 47,XXY) is the most common sex chromosome disorder in man, affecting approximately 1:660 men, and is a common cause of infertility.Patients with KS are characterized by tall stature and progressive testicular failure. This results in azoospermia and androgen deficiency with an accompanying risk of developing several phenotypic characteristics in adulthood, e.g., osteopenia or even frank osteoporosis, and metabolic syndrome.<...